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Search All Research Studies
Topics
- Back Health and Pain (1)
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- (-) Chronic Conditions (17)
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- Research Methodologies (1)
- Risk (1)
- Social Determinants of Health (4)
- Tobacco Use (1)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 17 of 17 Research Studies DisplayedRuderman SA, Odden MC, Webel AR
Tobacco smoking and pack-years are associated with frailty among people with HIV.
This study examines the association of frailty with tobacco smoking and pack-years among people with HIV (PWH). The authors identified 8,608 PWH across 6 Centers for AIDS Research Network of Integrated Clinical Systems (CNICS) sites who completed ≥2 patient-reported outcome assessments, including a frailty phenotype measuring unintentional weight loss, poor mobility, fatigue, and inactivity, scored 0-4. The authors measured smoking as baseline pack-years and time-updated never, former, or current use with cigarettes/day. They used Cox models to associate smoking with risk of incident frailty (score ≥3) and deterioration (frailty score increase by ≥2 points), adjusted for demographics, antiretroviral medication, and time-updated CD4 count. Mean follow-up period of PWH was 5.3 years, the mean age at baseline was 45 years, 15% were female, and 52% were non-White. At baseline, 60% reported current or former smoking and both were associated with higher incident frailty risk, as was higher pack-years. Current smoking (among younger PWH) and pack-years were associated with higher risk of deterioration, but not former smoking.
AHRQ-funded; HS026154.
Citation: Ruderman SA, Odden MC, Webel AR .
Tobacco smoking and pack-years are associated with frailty among people with HIV.
J Acquir Immune Defic Syndr 2023 Oct 1; 94(2):135-42. doi: 10.1097/qai.0000000000003242..
Keywords: Tobacco Use, Human Immunodeficiency Virus (HIV), Chronic Conditions, Health Status
Thomson J, Hall M, Nelson K
Timing of co-occurring chronic conditions in children with neurologic impairment.
Children with neurologic impairment (NI) are at risk for developing co-occurring chronic conditions, increasing their medical complexity and morbidity. In this study, the authors assessed the prevalence and timing of onset for those conditions in children with NI. They concluded that children with NI enrolled in Medicaid had substantial multimorbidity that developed early in life.
AHRQ-funded; HS025138.
Citation: Thomson J, Hall M, Nelson K .
Timing of co-occurring chronic conditions in children with neurologic impairment.
Pediatrics 2021 Feb;147(2):e2020009217. doi: 10.1542/peds.2020-009217..
Keywords: Children/Adolescents, Neurological Disorders, Chronic Conditions, Medicaid, Health Status
Odlum M, Moise N, Kronish IM
Trends in poor health indicators among Black and Hispanic middle-aged and older adults in the United States, 1999-2018.
This study used records extracted from the Behavioral Risk Factor Surveillance System to determine which health indicators have improved or became worse among Black and Hispanic middle-aged (45 and older) adults compared to Whites from 1999 to 2018. This data is required by the Minority Health and Health Disparities Research and Education Act of 2000. A sample included of 4,856,326 participants, of them 60.9% women, mean age 60.4. During the last 20 years, Black adults showed an overall decrease showing improvement in uninsured status and physical inactivity while showing an overall increase in hypertension, diabetes, asthma, and stroke, and also the same increases and decreases in the Black-White gap. Hispanic adults showed improvement in physical inactivity and perceived poor health, while they showed overall deterioration in hypertension and diabetes. The Hispanic-White gap improved in coronary heart disease, stroke, kidney disease, asthma, arthritis, depression and physical inactivity while it increased for diabetes, hypertension, and uninsured status.
AHRQ-funded; HS025198.
Citation: Odlum M, Moise N, Kronish IM .
Trends in poor health indicators among Black and Hispanic middle-aged and older adults in the United States, 1999-2018.
JAMA Netw Open 2020 Nov 2;3(11):e2025134. doi: 10.1001/jamanetworkopen.2020.25134..
Keywords: Elderly, Racial and Ethnic Minorities, Disparities, Health Status, Health Insurance, Diabetes, Blood Pressure, Chronic Conditions
Rundell SD, Resnik L, Heagerty PJ
Comparing the performance of comorbidity indices in predicting functional status, health-related quality of life, and total health care use in older adults with back pain.
The purpose of this prospective cohort study was to determine how well the functional comorbidity index (FCI) predicted outcomes in older adults with back pain compared to Quan's modification of the Charlson comorbidity index (Quan-Charlson comorbidity index) and the Elixhauser comorbidity index. The investigators concluded that all indices performed similarly in predicting outcomes. The authors indicated that there is still a need to develop better function-based risk-adjustment models that improve prediction of functional outcomes versus standard comorbidity indices.
AHRQ-funded; HS019222; HS022972.
Citation: Rundell SD, Resnik L, Heagerty PJ .
Comparing the performance of comorbidity indices in predicting functional status, health-related quality of life, and total health care use in older adults with back pain.
J Orthop Sports Phys Ther 2020 Mar;50(3):143-48. doi: 10.2519/jospt.2020.8764..
Keywords: Elderly, Back Health and Pain, Pain, Chronic Conditions, Quality of Life, Healthcare Utilization, Health Status
Huguet N, Angier H, Hoopes MJ
Prevalence of pre-existing conditions among community health center patients before and after the Affordable Care Act.
Investigators assessed the prevalence of pre-existing conditions for community health center (CHC) patients who gained insurance coverage post-Affordable Care Act (ACA). They found that their study emphasized the high prevalence of pre-existing conditions among CHC patients and the large increase in the proportion of patients with at least one of these diagnoses post-ACA. They conclude that, given how common these conditions are, repealing pre-existing condition protections could be extremely harmful to millions of patients and would likely exacerbate health care and health disparities.
AHRQ-funded; HS024270.
Citation: Huguet N, Angier H, Hoopes MJ .
Prevalence of pre-existing conditions among community health center patients before and after the Affordable Care Act.
J Am Board Fam Med 2019 Nov-Dec;32(6):883-89. doi: 10.3122/jabfm.2019.06.190087..
Keywords: Health Status, Chronic Conditions, Health Insurance, Policy
Wisk LE, Weitzman ER
Expectancy and achievement gaps in educational attainment and subsequent adverse health effects among adolescents with and without chronic medical conditions.
This study sought to investigate educational aspirations, expectations, and attainment among youth with and without chronic conditions and to determine if these relationships mediated subsequent disparities in health and well-being. Findings suggest an important risk mechanism through which youth with chronic medical conditions may acquire socioeconomic disadvantage as they develop and progress through educational settings.
AHRQ-funded; HS022986; HS000063.
Citation: Wisk LE, Weitzman ER .
Expectancy and achievement gaps in educational attainment and subsequent adverse health effects among adolescents with and without chronic medical conditions.
J Adolesc Health 2017 Oct;61(4):461-70. doi: 10.1016/j.jadohealth.2017.04.006..
Keywords: Children/Adolescents, Chronic Conditions, Disparities, Education, Health Status
Karter AJ, Lipska KJ, O'Connor PJ
High rates of severe hypoglycemia among African American patients with diabetes: the Surveillance, Prevention, and Management of Diabetes Mellitus (SUPREME-DM) network.
This seven-year surveillance study (2005-2011) evaluated race/ethnic differences in the trends in rates of severe hypoglycemia (SH) in a population of insured, at-risk adults with diabetes. Annual SH rates ranged from 1.8 percent to 2.1 percent during this 7-year observation period. African Americans had consistently higher SH rates compared with Whites, while Latinos and Asians had consistently lower rates compared with Whites in each of the 7 years.
AHRQ-funded; HS019859.
Citation: Karter AJ, Lipska KJ, O'Connor PJ .
High rates of severe hypoglycemia among African American patients with diabetes: the Surveillance, Prevention, and Management of Diabetes Mellitus (SUPREME-DM) network.
J Diabetes Complications 2017 May;31(5):869-73. doi: 10.1016/j.jdiacomp.2017.02.009.
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Keywords: Chronic Conditions, Diabetes, Healthcare Delivery, Health Status, Racial and Ethnic Minorities
Chang SH, Yu YC, Carlsson NP
Racial disparity in life expectancies and life years lost associated with multiple obesity-related chronic conditions.
This study investigated racial disparity in life expectancies (LEs) and life years lost associated with multiple obesity-related chronic conditions. It found that black individuals had higher risks of developing diabetes, hypertension, and stroke. This disparity in LE between white and black participants was largest in men age 40 to 49 with at least stroke: black men lived 3.12 years shorter than white men.
AHRQ-funded; HS022330.
Citation: Chang SH, Yu YC, Carlsson NP .
Racial disparity in life expectancies and life years lost associated with multiple obesity-related chronic conditions.
Obesity 2017 May;25(5):950-57. doi: 10.1002/oby.21822.
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Keywords: Chronic Conditions, Disparities, Health Status, Medical Expenditure Panel Survey (MEPS), Obesity, Racial and Ethnic Minorities
Jackson BE, Oates GR, Singh KP
Disparities in chronic medical conditions in the Mid-South.
This study examined differences in socio-demographic characteristics and health behaviors relevant to chronic medical conditions (CMCs) in the Mid-South region (Alabama, Mississippi, Louisiana, Kentucky, Tennessee, and Arkansas), and identified subpopulations with increased burden of chronic disease. It concluded that in the Mid-South, race and gender disparities in the top five chronic conditions are more prominent among higher-income rather than lower-income individuals.
AHRQ-funded; HS023009.
Citation: Jackson BE, Oates GR, Singh KP .
Disparities in chronic medical conditions in the Mid-South.
Ethn Health 2017 Apr;22(2):196-208. doi: 10.1080/13557858.2016.1232805.
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Keywords: Chronic Conditions, Disparities, Health Status, Racial and Ethnic Minorities, Social Determinants of Health
Oates GR, Jackson BE, Partridge EE
Sociodemographic patterns of chronic disease: how the mid-south region compares to the rest of the country.
This descriptive study examines sociodemographic differences in the distribution of chronic diseases and health-related behaviors in the Mid-South versus the rest of the U.S., identifying subgroups at increased risk of chronic disease. It finds that the Mid-South population had increased rates of chronic disease and worse health-related behaviors than the rest of the U.S. Mid-South blacks had the highest percentages of obesity, diabetes, high blood pressure, and stroke of all subgroups.
AHRQ-funded; HS023009.
Citation: Oates GR, Jackson BE, Partridge EE .
Sociodemographic patterns of chronic disease: how the mid-south region compares to the rest of the country.
Am J Prev Med 2017 Jan;52(1s1):S31-s39. doi: 10.1016/j.amepre.2016.09.004.
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Keywords: Chronic Conditions, Health Status, Lifestyle Changes, Social Determinants of Health
Cockerham WC, Hamby BW, Oates GR
The social determinants of chronic disease.
This review article addresses the concept of the social determinants of health (SDH), selected theories, and its application in studies of chronic disease. The health effects of SDH are initially discussed with respect to smoking and the social gradient in mortality. The article concludes with an examination of neighborhood disadvantage, social networks, and perceived discrimination in SDH research.
AHRQ-funded; HS023009.
Citation: Cockerham WC, Hamby BW, Oates GR .
The social determinants of chronic disease.
Am J Prev Med 2017 Jan;52(1s1):S5-s12. doi: 10.1016/j.amepre.2016.09.010.
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Keywords: Chronic Conditions, Health Status, Lifestyle Changes, Social Determinants of Health
Kenzik KM, Kent EE, Martin MY
Chronic condition clusters and functional impairment in older cancer survivors: a population-based study.
The purpose of this study was to identify chronic condition clusters at pre- and post-cancer diagnosis, evaluate predictors of developing clusters post-cancer, and examine the impact on functional impairment among older cancer survivors. It found that distinct condition clusters of two or more chronic conditions are prevalent among older cancer survivors. Cluster prevalence increases from pre- to post-cancer diagnosis.
AHRQ-funded; HS023009; HS013852.
Citation: Kenzik KM, Kent EE, Martin MY .
Chronic condition clusters and functional impairment in older cancer survivors: a population-based study.
J Cancer Surviv 2016 Dec;10(6):1096-103. doi: 10.1007/s11764-016-0553-4.
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Keywords: Chronic Conditions, Cancer, Elderly, Research Methodologies, Health Status
Koroukian SM, Schiltz N, Warner DF
Combinations of chronic conditions, functional limitations, and geriatric syndromes that predict health outcomes.
The researchers aimed to identify combinations of chronic conditions, functional limitations, and geriatric syndromes that predict poor health outcomes. They found that functional limitations and/or geriatric syndromes were the most prominent conditions in predicting health outcomes. They concluded that accounting for chronic conditions alone may be less informative than also accounting for the co-occurrence of functional limitations and geriatric syndromes, as the latter conditions appear to drive health outcomes in older individuals.
AHRQ-funded; HS023113.
Citation: Koroukian SM, Schiltz N, Warner DF .
Combinations of chronic conditions, functional limitations, and geriatric syndromes that predict health outcomes.
J Gen Intern Med 2016 Jun;31(6):630-7. doi: 10.1007/s11606-016-3590-9.
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Keywords: Elderly, Chronic Conditions, Risk, Outcomes, Health Status
Hannum SM, Rubinstein RL
The meaningfulness of time; narratives of cancer among chronically ill older adults.
The authors sought to describe how chronically ill older adults experience a new cancer diagnosis and the effects of this on their interpretations of personal health, aging, and the future. Among the fifteen participants, they found that perceived time was fragmented into three distinct segments: the Recalled Past, the Existent Present, and the Imagined Future. They discussed implications for how older adults understood their cancer.
AHRQ-funded; HS020177.
Citation: Hannum SM, Rubinstein RL .
The meaningfulness of time; narratives of cancer among chronically ill older adults.
J Aging Stud 2016 Jan;36:17-25. doi: 10.1016/j.jaging.2015.12.006.
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Keywords: Elderly, Cancer, Chronic Conditions, Health Status
Batsis JA, Mackenzie TA, Lopez-Jimenez F
Sarcopenia, sarcopenic obesity, and functional impairments in older adults: National Health and Nutrition Examination Surveys 1999-2004.
The researchers tested the hypothesis that the prevalence of sarcopenia and sarcopenic obesity would be similar based on the different NIH criteria, increase with age, and be associated with risk of impairment limitations. They concluded that the prevalence of sarcopenia and sarcopenic obesity varies greatly, and a uniform definition is needed to identify and characterize these high-risk populations.
AHRQ-funded; HS021695.
Citation: Batsis JA, Mackenzie TA, Lopez-Jimenez F .
Sarcopenia, sarcopenic obesity, and functional impairments in older adults: National Health and Nutrition Examination Surveys 1999-2004.
Nutr Res 2015 Dec;35(12):1031-9. doi: 10.1016/j.nutres.2015.09.003.
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Keywords: Elderly, Obesity, Chronic Conditions, Health Status
Thorpe RJ, Jr., Bell CN, Kennedy-Hendricks A
Disentangling race and social context in understanding disparities in chronic conditions among men.
This study compared survey data collected in 2003 from black and white men with similar incomes living in a racially integrated neighborhood of Baltimore to data from the 2003 National Health Interview Survey. The researchers found no race disparities in chronic conditions among low-income, urban men living in the same social environment, and they recommended that policies and interventions aiming to reduce disparities in chronic conditions focus on modifying social aspects of the environment.
AHRQ-funded; HS000029.
Citation: Thorpe RJ, Jr., Bell CN, Kennedy-Hendricks A .
Disentangling race and social context in understanding disparities in chronic conditions among men.
J Urban Health 2015 Feb;92(1):83-92. doi: 10.1007/s11524-014-9900-9.
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Keywords: Chronic Conditions, Disparities, Health Status, Racial and Ethnic Minorities, Social Determinants of Health
McGuire TG, Newhouse JP, Normand SL
AHRQ Author: Zuvekas S
Assessing incentives for service-level selection in private health insurance exchanges.
The authors used MEPS data to measure plan incentives by constructing predictive ratios and by measuring incentives based on the predictability and predictiveness of various medical diagnoses. They found that, among the chronic diseases studied, plans have the greatest incentive to skimp on care for cancer, mental health, and substance abuse.
AHRQ-authored.
Citation: McGuire TG, Newhouse JP, Normand SL .
Assessing incentives for service-level selection in private health insurance exchanges.
J Health Econ 2014 May;35:47-63. doi: 10.1016/j.jhealeco.2014.01.009.
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Keywords: Chronic Conditions, Health Insurance, Health Status, Medical Expenditure Panel Survey (MEPS)