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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 4 of 4 Research Studies DisplayedKulhawy-Wibe SC, Zell J, Michaud K
Systematic review and appraisal of the cross-cultural validity of functional status assessment measures in rheumatoid arthritis.
Researchers conducted a systematic review and appraisal of the cross-cultural adaptation and cross-cultural validity of the Health Assessment Questionnaire and its derivatives, and of the more recent Patient-Reported Outcomes Measurement Information System (PROMIS) functional status assessment measures (FSAMs) in rheumatoid arthritis. They concluded that their review highlighted a paucity of data on the cross-cultural validity of FSAMs and the mostly poor- or fair-quality methods by which they were translated and adapted.
AHRQ-funded; HS025638.
Citation: Kulhawy-Wibe SC, Zell J, Michaud K .
Systematic review and appraisal of the cross-cultural validity of functional status assessment measures in rheumatoid arthritis.
Arthritis Care Res 2020 Jun;72(6):798-805. doi: 10.1002/acr.23904..
Keywords: Arthritis, Cultural Competence, Health Status
Barber CEH, Zell J, Yazdany J
2019 American College of Rheumatology recommended patient-reported functional status assessment measures in rheumatoid arthritis.
This study’s objective was to develop American College of Rheumatology (ACR) Functional Status Assessment Measures (FSAMs) for patient reporting in most clinic settings. The authors convened a workgroup to conduct a systematic literature review through March 2017. They focused on the following FSAMs: the Health Assessment Questionnaire (HAQ) and derived measures from the Patient-Reported Outcomes Measurement Information System (PROMIS) tool. Out of 11,835 articles identified in the search, 56 were included in the review. A modified Delphi process identified 7 measures which fulfilled the minimum standard for regular use, and 3 measures were recommended: the PROMIS 10-item short form, the HAQ-II, and the Multidimensional HAQ.
AHRQ-funded; HS025638.
Citation: Barber CEH, Zell J, Yazdany J .
2019 American College of Rheumatology recommended patient-reported functional status assessment measures in rheumatoid arthritis.
Arthritis Care Res 2019 Dec;71(12):1531-39. doi: 10.1002/acr.24040..
Keywords: Arthritis, Health Status, Guidelines, Evidence-Based Practice
Gianfrancesco MA, Yazdany J, Schmajuk G
The impact of smoking on disease measures in rheumatoid arthritis: the need for appropriate adjustment of time-varying confounding.
In a recent publication, Quintana-Dunque et al. studied patients with early onset rheumatoid arthritis (RA) and showed that baseline smoking status was inversely associated with disease activity and disability at 36 months. This paper argues that the authors failed to highlight several limitations of study design and analysis, including time-varying confounding, which may have had a direct impact on results and corresponding conclusions.
AHRQ-funded; HS024412.
Citation: Gianfrancesco MA, Yazdany J, Schmajuk G .
The impact of smoking on disease measures in rheumatoid arthritis: the need for appropriate adjustment of time-varying confounding.
Rheumatol Int 2018 Feb;38(2):313-14. doi: 10.1007/s00296-017-3902-3.
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Keywords: Health Status, Lifestyle Changes, Arthritis, Tobacco Use
Curtis JR, Yang S, Chen L
Determining the minimally important difference in the Clinical Disease Activity Index for improvement and worsening in early rheumatoid arthritis patients.
This study determined the amount of change in the Clinical Disease Activity Index (CDAI) that represented improvement and worsening minimum clinically important differences (MCIDs). The optimal cut point for the MCID for CDAI improvement stratified for baseline disease activity was a change of 12 (high disease activity), 6 (moderate disease activity), and 1 (low disease activity). The MCID for CDAI worsening among RA patients who achieved low disease activity was 2 units.
AHRQ-funded; HS018517.
Citation: Curtis JR, Yang S, Chen L .
Determining the minimally important difference in the Clinical Disease Activity Index for improvement and worsening in early rheumatoid arthritis patients.
Arthritis Care Res 2015 Oct;67(10):1345-53. doi: 10.1002/acr.22606..
Keywords: Arthritis, Health Status